Perinatal stress and early brain development

Supervised by: Dr Michael Craig, Dr Suresh Victor, Prof Serena Counsell

 

My PhD project is focused on investigating the relationship between maternal stress (anxiety and depression) and fetal/neonatal brain development. This study is part of the developing Human Connectome Project (dHCP), which aims to map the growth of the baby's brain during pregnancy and how it continues to develop after birth. 

Find out more about the dHCP at http://www.developingconnectome.org/

Fetal scan

Neonatal scan

EDiTS Study

Early Development in Tuberous Sclerosis study - Research Assistant (2018-2019)

Supervised by: Dr Charlotte Tye

 

The aim of the Early Development in Tuberous Sclerosis (EDiTS) Study is to better understand how the development of babies with TSC differs to typically developing babies, and how sudden changes in seizure severity and treatment affect development.

Find out more about EDiTS at: https://www.edits-study.org/

IDEAS Study

Individual Differences in EEG in young adults  - Research Assistant (2016-2017)

Supervised by: Dr Grainne McLoughlin, Dr Alex Lau-Zhu

 

The aim of the IDEAS study is to investigate the development of young adults with Autism Spectrum Disorder and/or ADHD in twin sample from TEDS (Twins Early Development Study) using mobile EEG. 

Find out more about IDEAS at: https://www.ideas-kcl.co.uk/

DiDS Study

Dementia in Down syndrome study - MPhil Student (2014-2015)

Supervised by: Prof Tony Holland, Dr Shahid Zaman 

 

The DiDS Study aims to investigate the development of Alzheimer's disease in people with Down syndrome. My MPhil was focused on mitochondrial dysfunction as an early indicator of dementia in this population. 

Find out more about DiDS at: http://www.psychiatry.cam.ac.uk/ciddrg/research/dementia-in-downs-syndrome-dids/​

Experience outside of research

Dementia Support Worker - Alzheimer's Society (Oct 2015 - May 2016)

Drug Support Worker - Devon Drug Service (Nov 2013 - May 2014)

Special Needs Counsellor - Camp Horizons USA (June 2013 - Sept 2013)

Research experience and training

Imaging: MRI, (mobile) EEG, eye tracking

Data analysis

      Programming languages: R (intermediate), Python (basic), Matlab (basic), Bash (basic)

      Other software: FSL, MRTrix3, Paraview, DTITK, ITKSnap, SPSS

 

Expertise: Autism, Down syndrome,  Dementia, ADHD, Depression, Anxiety, early development 

Assessments: 

      Toddlers and Children ​

       ADOS-2: Autism Diagnostic Observation Schedule 

       Mullen Scales of Early Learning

       Vineland Adaptive Behaviour Scales 

       Structured free play

            

      Adults 

       ADOS-2: Autism Diagnostic Observation Schedule 

       DIVA: Diagnostic Interview for ADHD in Adults

       MINI: Mini International Psychiatric Interview 

       SOFAS: Social and Occupational Functioning Assessment Scale 

      Older adults with Down Syndrome

       CAMDEX-DS: Cambridge Examination for Mental Disorders of Older People with Down Syndrome 

       CAMCOG-DS: Cambridge Cognition Examination in people with Down Syndrome

       SIB: Severe Impairment Battery 

       ACTB: Arizona Cognitive Test Battery 

       CANTAB: Cambridge Automated Neuropsychological Test Automated Battery 

       Table top tests: Tower of London, Weigl sorting task, Spatial reversal, Scrambled boxes, Cats and dogs, Oliver                                   memory test for sentences, Oliver object memory​, Verbal fluency for animals

 

                           

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CONTACT:

Email                        alexandra.lautarescu@kcl.ac.uk

Twitter                     @AleLautarescu 

Correspondence      Centre for Developing Brain 

                                  King's College London 

                                  1st floor, South Wing, St Thomas' Hospital 

                                  London, SE1 7EH

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